Short Communication
Anticancer Activity of Genistin: A Short Review
Md Mizanur Rahaman*, Md Iqbal Sikder and Muhammad Ali Khan and Muhammad Torequl Islam
Published: 16 June, 2023 | Volume 7 - Issue 1 | Pages: 010-013
Genistein is an isoflavone glycoside that provides a variety of health advantages. The possibility of cancer chemopreventive drugs derived from natural sources, such as polyphenols, may constitute a novel, cost-effective strategy to reduce the rising burden of cancer throughout the world. A soy-rich diet was linked to cancer prevention in several epidemiological studies, which was explained by the presence of the phenolic component genistein in soy-based foods. Inhibiting metastasis and changing apoptosis, the cell cycle, and angiogenesis are the key ways that genistin fights various cancers. It acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis. This study critically evaluates the literature that is currently available on the therapeutic benefits of genistin for various cancers.
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DOI: 10.29328/journal.acst.1001035
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Keywords:
Genistin; Cancer; Isoflavone protective effect
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