Research Article
Published: 14 January, 2019 | Volume 3 - Issue 1 | Pages: 001-024
Many pathologic disease can be considered as related to an Endogenous toxicological moves and in time dependent way (kinetics and dynamic of the process). In this work starting from the analysis of relevant literature involved with different disease and related to the endogenous local micro- environment some global conclusion useful as new tools for innovative pharmacological strategies will be submitted to the researcher. Physiology, pathology concept linked to the endogenous toxicological local micro-environment status as new research instruments. The same carcinogenesis process can be related also to endogenous agents that may have a major contribution in spontaneously process. (Reactive oxygen species (ROS), which are involved in multiple cellular processes by physiologically transporting signal as a second messenger or pathologically oxidizing DNA, lipids, and proteins).
Read Full Article HTML DOI: 10.29328/journal.acst.1001004 Cite this Article Read Full Article PDF
Endogenous toxicology; Physiology; Pharmacological strategies; New pathogenetic theories; Cancer; Metastasys
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